Macromolecular Crystallography
Macromolecular Crystallography is a technique to investigate biological molecules such as proteins, viruses, and nucleic acids (RNA and DNA) with high-resolution imaging.
The high resolution boosts the ability of the researcher to elucidate detailed mechanisms by which these macromolecules carry out their functions in living cells and organisms.
The picture Illustrated represents the trypsin Crystal diffraction structure. The experiment was done at the LNLS MX2 beamline. MX2 beamline was an experimental station dedicated to Macromolecular Crystallography in the hard x-rays energy range (5 to 15 keV) with maximum flux at 8.5 keV.
Link: https://www.lnls.cnpem.br/facilities/mx2-en
Detector used at experiment: PIMEGA 135D: https://www.pitec.co/pimega-135d
Credits: Andrey Nascimento and Ana Zeri
Macromolecular Crystallography use case
A Courtesy of the LNLS-Sirius @CNPEM, Brazil
LNLS MX2 Beamline, Detector: PIMEGA 135D, Sensor: Si / 300µm, Experiment goal: Trypsine crystal structure image
Credits: Andrey Nascimento and Ana Zeri
